Abstract: A total of 30 pairs of binary hybrids (Changbai × Dabai) boars with weaning at 34±1 days and weighing 8.7±0.8kg were selected to study the growth performance of the diet with the addition of organic glycine copper phase with the copper sulfate in the weaned piglets. The effects of blood physiological and biochemical indicators and the content of copper in plasma and tissues. The pigs were randomly divided into three groups according to their body weight and nest. They were fed with 15 (n=6) and 250 mg/kg copper from copper sulfate (n=12) and 250 mg/kg. Pigs derived from copper glycinate (n=12) were housed in a metabolic cylinder with no elemental contamination in the metabolic chamber (22. 5 °C). On the 28th day of the official trial period, pigs were only allowed to eat and drink tap water freely. Between 3 treatment groups, pig growth rate, feed intake, feed conversion ratio, hemoglobin concentration, hematocrit, plasma biochemical indicators (total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglyceride and urea ammonia) There was no significant difference in copper content in plasma, pancreas, kidney and spleen (p>0.1). Compared with the control group supplemented with 15mg/kg copper from copper sulfate, the addition of 250mg/kg copper was derived from copper sulfate. Both copper and glycine copper treatment groups significantly increased the copper content in the brain, liver and myocardium of weaned piglets (p<0.05), but there was no significant difference between the two high copper levels in the copper source treatment group (p>0.60). . The results of this study show that organic glycine copper and inorganic copper sulfate are equally effective for weaned piglets. Key words: copper glycinate; tissue copper; weaned piglet CLC number: S82815 Document code: A Article ID: 0366- 6964 (2004) 01-0023-05 The necessity of trace element copper for animal and plant nutrition was reported by McHargue (1952) [1]. As a general essential nutrient element, pigs need only about 5 mg/kg of copper [2]. But Braude (1945) [3] first observed that pigs have a desire for copper. Barker et al. (1955) [4] found that the addition of 250 mg/kg of copper to pig diet significantly promoted pig growth. A large number of experimental studies have confirmed this conclusion [5-9]. High-dose copper (125~250mg/kg, especially 250mg/kg) is a highly effective and inexpensive growth-promoting additive for pig diets. It has been used in pig production in other countries for more than 40 years and is currently raised in China. The application in the pig industry is also quite common [10]. Since the apparent absorption rate of copper to pigs is between 5% and 20% [11], a large amount of unabsorbed copper is discharged from the surface with the surface, causing potential pollution to the environment. Recent studies have found that the growth-promoting effect of copper on pigs is likely to be systemic, not just the antimicrobial effects previously thought to be limited to the gastrointestinal tract [9-10]. Therefore, the development and application of a new type of copper source for efficient absorption and utilization in the growth of pigs, in order to maximize the copper-to-pig growth-promoting effect, while reducing the environmental pollution caused by copper discharge, is attracting great interest and widespread concern. Therefore, there are more and more researches on the biological utilization of pigs with different forms of copper sources (mainly organic amino acid copper sources relative to the endless copper sulfate source). In the study of copper source bioavailability evaluation, most of the copper sulfate was used as the reference standard, and the liver content was used as the evaluation index. Coffey et al. (1994) [8] reported that 100 mg/kg of copper originated from a copper sulfate source, but the liver copper content was lower than that of a copper sulfate source. Kuznetsov et al. (1987) [11] considered that the most effective form of copper is casein copper, followed by copper propionate and copper acetate, and the biological utilization rate is 170%, 152%, and 142% of copper sulfate. Glycine is the smallest molecule of all amino acids. Theoretically, a copper ammonium complex (or chelate) formed from glycine and divalent copper ions is more susceptible to penetrating animal intestinal epithelial mucosal cells than all other amino acid copper complexes (or chelate compounds). It is fully absorbed and utilized. However, there have been no reports on the application of copper glycinate in pigs and the biological activity of inorganic copper sulfate. This experiment attempts to provide a scientific basis for the development and application of high-efficiency biologically active new organic copper sources in pig production in China through the special application of copper glycinate in pigs to the biological activity of inorganic copper sulfate. Pesticide D-Cyphenothrin,Pesticide Insecticide,Pesticide Agrochemicals Plastic Materials Co., Ltd. , http://www.hbpolypropylene.com